The Tennessee Titans (7-4) play at the Philadelphia Eagles (10-1) in an NFL battle of division leaders and the Kansas City Chiefs (9-2) play at the Cincinnati Bengals (7-4) on Sunday in a rematch of last season’s AFC Championship Game.
And one the league’s most intense rivalries resumes when the Green Bay Packers (4-8) and Chicago Bears (3-9) meet for the 206th time, most in NFL history.
Here’s everything you need to know about the NFL odds for Week 13 — the point spread, moneyline and total Over/Under (with all NFL odds via FOX Bet).
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All times ET
Teams with a bye: Cardinals, Panthers
THURSDAY’S GAME
Bills at Patriots (8:15 p.m., Amazon Prime Video)
Point spread: Bills -4.5 (Bills favored to win by more than 4.5 points, otherwise Patriots cover)
Moneyline: Bills -227 favorites to win (bet $10 to win $14.41 total); Patriots +175 underdogs to win (bet $10 to win $27.50 total)
Total scoring Over/Under: 43.5 points scored by both teams combined
SUNDAY’S GAMES
Steelers at Falcons (1 p.m., CBS)
Point spread: Falcons -1.5 (Falcons favored to win by more than 1.5 points, otherwise Steelers cover)
Moneyline: Falcons -125 favorites to win (bet $10 to win $18 total); Steelers +100 underdogs to win (bet $10 to win $20 total)
Total scoring Over/Under: 42 points scored by both teams combined
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Packers at Bears (1 p.m., FOX)
Point spread: Packers -3 (Packers favored to win by more than 3 points, otherwise Bears cover)
Moneyline: Packers -149 favorites to win (bet $10 to win $17.71 total); Bears +115 underdogs to win (bet $10 to win $21.50 total)
Total scoring Over/Under: 42.5 points scored by both teams combined
Jaguars at Lions (1 p.m., FOX)
Point spread: Lions -1.5 (Lions favored to win by more than 1.5 points, otherwise Jaguars cover)
Moneyline: Lions -118 favorites to win (bet $10 to win $18.47 total); Jaguars -105 underdogs to win (bet $10 to win $19.52 total)
Total scoring Over/Under: 51.5 points scored by both teams combined
Point spread: Vikings -3 (Vikings favored to win by more than 3 points, otherwise Jets cover)
Moneyline: Vikings -162 favorites to win (bet $10 to win $16.17 total); Jets +125 underdogs to win (bet $10 to win $22.50 total)
Total scoring Over/Under: 45.5 points scored by both teams combined
Commanders at Giants (1 p.m., FOX)
Point spread: Commanders -1.5 (Commanders favored to win by more than 1.5 points, otherwise Giants cover)
Moneyline: Commanders -133 favorites to win (bet $10 to win $17.52 total); Giants +105 underdogs to win (bet $10 to win $20.50 total)
Total scoring Over/Under: 40.5 points scored by both teams combined
Titans at Eagles (1 p.m., FOX)
Point spread: Eagles -5.5 (Eagles favored to win by more than 5.5 points, otherwise Titans cover)
Moneyline: Eagles -227 favorites to win (bet $10 to win $14.41 total); Titans +175 underdogs to win (bet $10 to win $27.50 total)
Total scoring Over/Under: 44.5 points scored by both teams combined
Broncos at Ravens (1 p.m., CBS)
Point spread: Ravens -8.5 (Ravens favored to win by more than 8.5 points, otherwise Broncos cover)
Moneyline: Ravens -400 favorites to win (bet $10 to win $12.50 total); Broncos +280 underdogs to win (bet $10 to win $38 total)
Total scoring Over/Under: 38.5 points scored by both teams combined
Browns at Texans (1 p.m., CBS)
Point spread: Browns -7 (Browns favored to win by more than 7 points, otherwise Texans cover)
Moneyline: Browns -303 favorites to win (bet $10 to win $13.30 total); Texans +220 underdogs to win (bet $10 to win $32 total)
Total scoring Over/Under: 47.5 points scored by both teams combined
Seahawks at Rams (4:05 p.m., FOX)
Point spread: Seahawks -7.5 (Seahawks favored to win by more than 7.5 points, otherwise Rams cover)
Moneyline: Seahawks -345 favorites to win (bet $10 to win $12.90 total); Rams +260 underdogs to win (bet $10 to win $36 total)
Total scoring Over/Under: 41.5 points scored by both teams combined
Dolphins at 49ers (4:05 p.m., FOX)
Point spread: 49ers -3.5 (49ers favored to win by more than 3.5 points, otherwise Dolphins cover)
Moneyline: 49ers -189 favorites to win (bet $10 to win $15.29 total); Dolphins +145 underdogs to win (bet $10 to win $24.50 total)
Total scoring Over/Under: 46.5 points scored by both teams combined
Chiefs at Bengals (4:25 p.m., CBS)
Point spread: Chiefs -2.5 (Chiefs favored to win by more than 2.5 points, otherwise Bengals cover)
Moneyline: Chiefs -138 favorites to win (bet $10 to win $17.25 total); Bengals +110 underdogs to win (bet $10 to win $21 total)
Total scoring Over/Under: 52.5 points scored by both teams combined
Chargers at Raiders (4:25 p.m., CBS)
Point spread: Chargers -1.5 (Chargers favored to win by more than 1.5 points, otherwise Raiders cover)
Moneyline: Chargers -133 favorites to win (bet $10 to win $17.52 total); Raiders +105 underdogs to win (bet $10 to win $20.50 total)
Total scoring Over/Under: 50.5 points scored by both teams combined
Colts at Cowboys (8:20 p.m., NBC)
Point spread: Cowboys -9.5 (Cowboys favored to win by more than 9.5 points, otherwise Colts cover)
Moneyline: Cowboys -455 favorites to win (bet $10 to win $12.20 total); Colts +280 underdogs to win (bet $10 to win $38 total)
Total scoring Over/Under: 43.5 points scored by both teams combined
MONDAY’S GAME
Saints at Buccaneers (8:15 p.m., ESPN)
Point spread: Buccaneers -3.5 (Buccaneers favored to win by more than 3.5 points, otherwise Saints cover)
Moneyline: Buccaneers -189 favorites to win (bet $10 to win $15.29 total); Saints +145 underdogs to win (bet $10 to win $24.50 total)
Total scoring Over/Under: 40 points scored by both teams combined
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